The next important Cannabinoid, following CBD, Cannabigerol (CBG) comprises a cannabinoid displayed in greater concentrations in Hemp which can curb the metabolic activity and intoxicating effects of THC. CBG, the regenerating molecule that can convert into CBD, THC or various cannabinoids has proved to be the most medicinal among the different cannabinoids.
All the key cannabinoids – CBD, THC, and CBC are biosynthesized from cannabigerol (CBG) by the speedy action of enzymes.
CBG – What It Is?
Cannabigerol (CBG), or the “parent” molecule is the initial cannabinoid generated by the hemp plant. It begins as cannabigerolic acid (CBGa), and upon exposure to heat or ultraviolet light, gets modified into CBG. CBG constitutes the “parent” of THC and CBD, and in truth, the medical advantages of CBG are a mix of-sorts of both, though not containing the psychoactive impact of THC.
CBG was found to stimulate neurogenesis (growth of brain cell), besides being antibacterial, anti-tumor, and assisting with insomnia. It is specifically non-toxic in comparison to most suggested pharmaceutical formulations and has no adverse effects.
CBG can regulate our body’s fight or flight stimulus. It can suppress the discharge of norepinephrine, which is stress hormones.
CBG is also believed to enhance anandamide, an endocannabinoid that normally reduces dopamine levels and controls different health functions like sleep, mood, and appetite. GABA uptake within the brain may be blocked by CBG, causing it to act like a probable muscle relaxant and anti-anxiety component. The blocking of serotonin receptors by CBG may also display potential antidepressant characteristics.
The Gum Disorder “Periodontitis”
Periodontitis, also termed gum disease, constitutes a general infection that harms the soft tissue plus bone holding the tooth. In the absence of treatment, the alveolar bone near the teeth is gradually and progressively destroyed.
The term “periodontitis” implies “inflammation near the tooth.” Microorganisms, like bacteria, adhere to the tooth’s surface and within the areas enclosing the tooth, and they propagate. With the reaction of the immune system and release of toxins, inflammation takes place.
Periodontitis will ultimately lead to tooth loss, in the absence of treatment. It might raise the danger of heart attack, stroke, and various health ailments.
Bacterial plaque, a gummy, colorless membrane that builds upon the teeth’s surface, is the prevalent cause of periodontal disease. The plaque can thicken to become tartar or calculus if it is not removed. Most instances of periodontitis are avoidable through proper dental hygiene.
Ways In Which CBG Can Treat Periodontitis
Periodontitis constitutes an advanced gum ailment caused by bacterial plaque, CBG can be effective in treating it due to its antibacterial properties. The antimicrobial effects of CBG are useful for treating antibiotic resistance which may also be applicable in the case of gum disorders. A special mention can be made of CBG’s prominent anti-bacterial properties which it exerts on the bacterium Staphylococcus aureus. CBG is well-recognized for its potential to treat an antibiotic-resistant bacteria known as MRSA (methicillin-resistant staphylococcus aureus).
As gingivitis can advance into periodontitis which causes severe gum inflammation, CBG can also redress such condition as it is anti-inflammatory in nature. The use of cannabinoids like CBD as well as CBG for oral care formulations to heal oral infections like periodontitis stems from its antibacterial effects. The analgesic properties of CBG helps to treat pain in periodontitis.
Our endocannabinoid mechanism that involves the receptors CB1 and CB2 regulates our physiological functions. Since CBG attaches itself to the CB2 receptor which is located in the immune system cells, thereby it can control the immune responses. Moreover, research has also presented that CBG can effectively block different compounds from attaching regulate with the CB1 receptor which is found in the brain.
CBG has made inroads into oral care and has become an active component in the dental line-up of toothpaste, oral rinses, dental floss, and oral gel. Moreover, it has emerged as an antimicrobial solution for preventing decay, plaque, and gingival irritation.
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